Everyone associates Steve Jobs with Apple and the Macintosh, but it was Steve Wozniak that made the intial magic happen with the Apple I & II. Here's an interview with Woz about those early days, and a book due out soon about him.
Andy Hertzfeld was another Apple hacker that worked on the Mac version 1 system software. He's got a website, folklore.org with loads of behind the scenes stories on the creation of the Mac. Here's a video of him giving a tech talk about the early Mac at his new company, Google.
NodeBox is a cool Mac OS X application that allows you to write python code and have it drawn by the application. NodeBox itself is written in python and comes with a collection of functions and libraries you can use, and even does animation (see the gallery here).
This is some really cool looking stuff. The artificial life simulations look awesome. Thanks for pointing this out. From what I can tell it uses python to generate PDF documents using Apple's display renderer. Pretty cool.